Document Detail


Silent ACTH cell adenoma in coincidence with granulomatous hypophysitis--a case report.
MedLine Citation:
PMID:  17395399     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 44-year-old male suffered from an inactive pituitary adenoma measuring 20mm in computed tomography (CT) scan and nuclear magnetic resonance tomography (NMR). The tumor was surgically resected via the transnasal-transsphenoidal route. Surgical specimens revealed a typical, sparsely granulated adrenocorticotropic hormone (ACTH) cell adenoma, but also a granulomatous inflammation mostly in the periphery of the tumor, corresponding to a granulomatous hypophysitis. This coincidence appears to be unique and has yet not been described in the literature. Therefore, the clinical data and the pathohistologic and ultrastructural findings are presented here.
Authors:
Wolfgang Saeger; Bernd M Hofmann; Rolf Buslei; Michael Buchfelder
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-03-29
Journal Detail:
Title:  Pathology, research and practice     Volume:  203     ISSN:  0344-0338     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  2007  
Date Detail:
Created Date:  2007-04-23     Completed Date:  2007-07-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  221-5     Citation Subset:  IM    
Affiliation:
Institute of Pathology of the Marienkrankenhaus Hamburg, Hamburg, Germany. saeger.patho@marienkrankenhaus.org
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MeSH Terms
Descriptor/Qualifier:
ACTH-Secreting Pituitary Adenoma / complications*,  ultrastructure*
Adenoma / complications*,  ultrastructure*
Adult
Brain Ischemia / complications
Granuloma / complications,  pathology
Humans
Immunohistochemistry
Incidental Findings
Magnetic Resonance Imaging
Male
Microscopy, Electron, Transmission
Pituitary Diseases / complications*,  pathology*
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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