| Sildenafil as a pulmonary vasodilator after repair of congenital heart disease. | |
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MedLine Citation:
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PMID: 18306725 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe successful use of enteral sildenafil following surgery for congenital heart disease in three cases. One infant after repair of ventricular septal defect and aortic coarctation had pulmonary hypertension non-responsive to nitric oxide, another infant and 3.5 year child following palliative surgery for congenital heart disease with univentricular physiology were treated with inhaled nitric oxide and had severe systemic desaturations associated with endotracheal suctioning. Therapy with sildenafil reduced pulmonary arterial pressure, prevented episodes of arterial desaturations and allowed weaning from nitric oxide (Ref. 7). Full Text (Free, PDF) www.bmj.sk |
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Authors:
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L Kovacikova; M Zahorec; M Nosal |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Bratislavské lekárske listy Volume: 108 ISSN: 0006-9248 ISO Abbreviation: Bratisl Lek Listy Publication Date: 2007 |
Date Detail:
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Created Date: 2008-02-29 Completed Date: 2008-04-22 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0065324 Medline TA: Bratisl Lek Listy Country: Slovakia |
Other Details:
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Languages: eng Pagination: 453-4 Citation Subset: IM |
Affiliation:
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Intensive Care Unit, Pediatric Cardiac Center, Bratislava, Slovakia. lkovacikova@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Heart Defects, Congenital / surgery* Humans Hypertension, Pulmonary / drug therapy*, etiology, physiopathology Infant Phosphodiesterase Inhibitors / therapeutic use* Piperazines / therapeutic use* Postoperative Complications* Purines / therapeutic use Sulfones / therapeutic use* Vascular Resistance Vasodilator Agents / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Phosphodiesterase Inhibitors; 0/Piperazines; 0/Purines; 0/Sulfones; 0/Vasodilator Agents; 139755-83-2/sildenafil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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