| Significant modification of lipid metabolism in aged persons following the treatment with a nutritive supplement containing embryonary peptides--preliminary results. | |
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MedLine Citation:
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PMID: 16739873 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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HUMANOFORT is a nutritive supplement extracted and purified from embryonated chicken eggs according to an original procedure under licence. Humanofort received the suitable consent from the Romanian Ministry of Health. The main components of Humanofort are two oligopeptides of 5,000 and 10,000 D molecular weight. 40 subjects aged 50-75 years (18 men and 22 women) consumed, daily, 4 caps of Humanofort for 60 days. The samples of blood from each subject were obtained before and after treatment. Therefore, each subject was his own control. In all subjects, after treatment, total cholesterol and LDL-cholesterol decreased approximately 30% as compared with the initial values. In 80% of patients, an increase of HDL cholesterol and a decrease of the insulin level in blood were also observed. After treatment, the cardiac risk factors (Aethna 2000 Program), such as total cholesterol/HDL and Apolipoproteins B/A were shifted towards lower range. These long-lasting modifications have an adaptative-regulatory character and seem to be produced by the growth factors contained in Humanofort. |
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Authors:
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G Mihăescu; R Olinescu; F Oancea |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Romanian journal of internal medicine = Revue roumaine de médecine interne Volume: 43 ISSN: 1220-4749 ISO Abbreviation: Rom J Intern Med Publication Date: 2005 |
Date Detail:
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Created Date: 2006-06-02 Completed Date: 2006-10-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9304507 Medline TA: Rom J Intern Med Country: Romania |
Other Details:
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Languages: eng Pagination: 133-9 Citation Subset: IM |
Affiliation:
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Hipocrate 2002-Serv. Trade Company, Prahova St. Bucharest 1, Romania. hip2002@zappmobile.ro |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Apolipoproteins / blood, drug effects Cholesterol / blood Cholesterol, LDL / blood Diabetes Mellitus / diet therapy Dietary Supplements Egg Proteins, Dietary / isolation & purification, pharmacology* Female Humans Lipid Metabolism / drug effects* Male Middle Aged Peptides / chemistry, isolation & purification, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Apolipoproteins; 0/Cholesterol, LDL; 0/Egg Proteins, Dietary; 0/Peptides; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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