| Significant medical pathology discovered during a male infertility evaluation. | |
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MedLine Citation:
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PMID: 11435851 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Because a pregnancy can be achieved without a male infertility evaluation, some have questioned its usefulness. However, by bypassing a urological evaluation the man might not learn the cause of infertility and not be offered specific corrective therapy. In addition, men with subfertility may have a serious underlying medical or genetic problem that could also be overlooked. We determine the incidence of significant medical pathology discovered during a male infertility evaluation at 2 academic infertility practices. MATERIALS AND METHODS: All men examined for either primary or secondary infertility were included in our study, while men seen for vasectomy reversal were not. All patients underwent evaluation, consisting of a complete history, physical examination, semen analysis, hormone testing, urinalysis and genetic testing when appropriate. RESULTS: Significant medical pathology was discovered in 33 of 536 (6%) patients. A total of 27 patients had genetic abnormalities, including cystic fibrosis mutations in 24 and karyotypic abnormalities in 3. Of the remaining 6 patients 1 had testis cancer, 1 prostate cancer, 3 diabetes mellitus and 1 hypothyroidism. CONCLUSIONS: Significant medical pathology can be detected by a male infertility evaluation. In addition to identifying the cause of infertility, the evaluation may uncover conditions that threaten the health of the male partner or any potential offspring. |
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Authors:
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P N Kolettis; E S Sabanegh |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of urology Volume: 166 ISSN: 0022-5347 ISO Abbreviation: J. Urol. Publication Date: 2001 Jul |
Date Detail:
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Created Date: 2001-07-03 Completed Date: 2001-08-09 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376374 Medline TA: J Urol Country: United States |
Other Details:
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Languages: eng Pagination: 178-80 Citation Subset: AIM; IM |
Affiliation:
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Division of Urology, University of Alabama at Birmingham, Birmingham, Alabama, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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complications,
diagnosis Adult Diabetes Mellitus, Type 2 / complications, diagnosis* Evaluation Studies as Topic Humans Infertility, Male / etiology* Male Physical Examination Prognosis Prostatic Neoplasms / complications, diagnosis* Retrospective Studies Risk Assessment Semen / cytology Testicular Neoplasms / complications, diagnosis* Urinalysis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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