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Significance of uteroplacental Doppler at midtrimester in patients with favourable obstetric history.
MedLine Citation:
PMID:  23025716     Owner:  NLM     Status:  Publisher    
Abstract OBJECTIVES: to reassess the usefulness of midtrimester uterine Doppler in low risk multiparous women. METHODS: we prospectively recruited low risk pregnant women at 20-22 weeks attending our clinic. Among those, women with a favourable obstetric history (group A) were distinguished from nulliparous (group B) and of each group we measured uterine artery Doppler (Pulsatility Index, PI). We evaluated the accuracy of uterine artery Doppler in the prediction of preeclampsia and small for gestational age (SGA) neonates. RESULTS: Between January 2009 and October 2010, 382 women were included in the study of which 147 in group A and 235 in group B. Overall, 26/382 (6.8%) women presented preeclampsia and SGA occurred in 59/382 (15.4%) cases. In our population at a 10% FPR uterine artery Doppler showed a Detection Rate of 19.2% for preeclampsia and of 37.3% for SGA, with a higher sensitivity for SGA neonates delivered ≤ vs >34 weeks (87% vs 29.4%). The univariable ROC curve by uterine artery PI yielded a significant prediction only for SGA in nulliparous women (AUC of 0.70; 95%CI 0.60-0.79). CONCLUSIONS: Our data confirmed that midtrimester uterine artery Doppler isn't an efficient strategy in anticipating the risk of pregnancy complications among low risk multiparous women.
Arcangeli Tiziana; Giorgetta Francesca; Farina Antonio; De Musso Francesca; Bellussi Federica; Salsi Ginevra; Montaguti Elisa; Pilu Gianluigi; Rizzo Nicola; Ghi Tullio
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-1
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1Department of Obstetrics and Gynaecology, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
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