| Significance of squamous cell carcinoma (SCC)-related antigens in cutaneous SCC. A preliminary report. | |
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MedLine Citation:
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PMID: 3606169 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The serum levels of squamous cell carcinoma (SCC)-related antigens (SCC-RAG) were assayed, utilizing the radioimmunoassay kit, in six patients with cutaneous SCC, two patients with Bowen's disease, 18 patients with other benign and malignant dermatoses, and six normal subjects. The SCC-RAG titers were significantly high in three patients with invasive SCC in whom primary tumors were either comparatively large or were associated with metastatic lesions, while they remained within the normal limit in patients with smaller-sized, nonmetastatic SCC, Bowen's disease, other non-SCC dermatoses, and in normal control subjects. The SCC-RAG titers, therefore, provided a useful tumor marker for cutaneous SCC, particularly in advanced stages. In such cases, the values were clearly correlated with tumor behaviors in response to or against treatments and with the development of metastasis. |
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Authors:
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H Yagi; K Danno; Y Maruguchi; M Yamamoto; S Imamura |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of dermatology Volume: 123 ISSN: 0003-987X ISO Abbreviation: Arch Dermatol Publication Date: 1987 Jul |
Date Detail:
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Created Date: 1987-07-29 Completed Date: 1987-07-29 Revised Date: 2008-03-17 |
Medline Journal Info:
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Nlm Unique ID: 0372433 Medline TA: Arch Dermatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 902-6 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antigens, Neoplasm / analysis* Bowen's Disease / blood*, immunology, pathology Carcinoembryonic Antigen / analysis Carcinoma, Squamous Cell / blood*, immunology, pathology Dermatitis / blood Humans Male Middle Aged Neoplasm Metastasis / pathology Skin Neoplasms / blood*, immunology, pathology |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Neoplasm; 0/Carcinoembryonic Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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