Document Detail


Significance of squamous cell carcinoma (SCC)-related antigens in cutaneous SCC. A preliminary report.
MedLine Citation:
PMID:  3606169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The serum levels of squamous cell carcinoma (SCC)-related antigens (SCC-RAG) were assayed, utilizing the radioimmunoassay kit, in six patients with cutaneous SCC, two patients with Bowen's disease, 18 patients with other benign and malignant dermatoses, and six normal subjects. The SCC-RAG titers were significantly high in three patients with invasive SCC in whom primary tumors were either comparatively large or were associated with metastatic lesions, while they remained within the normal limit in patients with smaller-sized, nonmetastatic SCC, Bowen's disease, other non-SCC dermatoses, and in normal control subjects. The SCC-RAG titers, therefore, provided a useful tumor marker for cutaneous SCC, particularly in advanced stages. In such cases, the values were clearly correlated with tumor behaviors in response to or against treatments and with the development of metastasis.
Authors:
H Yagi; K Danno; Y Maruguchi; M Yamamoto; S Imamura
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of dermatology     Volume:  123     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1987 Jul 
Date Detail:
Created Date:  1987-07-29     Completed Date:  1987-07-29     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  902-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Antigens, Neoplasm / analysis*
Bowen's Disease / blood*,  immunology,  pathology
Carcinoembryonic Antigen / analysis
Carcinoma, Squamous Cell / blood*,  immunology,  pathology
Dermatitis / blood
Humans
Male
Middle Aged
Neoplasm Metastasis / pathology
Skin Neoplasms / blood*,  immunology,  pathology
Chemical
Reg. No./Substance:
0/Antigens, Neoplasm; 0/Carcinoembryonic Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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