| Significance of release technology in tissue engineering. | |
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MedLine Citation:
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PMID: 16376824 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Regenerative medical therapy has been expected to compensate for the therapeutic disadvantages of reconstructive surgery and organ transplantation, as well as offering a new therapeutic strategy. The objective of regenerative medical therapy is to induce the repair of defective tissues based on the natural healing potential of patients. For successful tissue regeneration, it is indispensable to provide cells with a local environment of artificial extracellular matrix where they can proliferate and differentiate efficiently. Tissue engineering is the key to this regeneration environment; release technology often enhances the in vivo stability of growth factors and related genes and prolongs the maintenance of biological functions for tissue regeneration. |
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Authors:
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Yasuhiko Tabata |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Drug discovery today Volume: 10 ISSN: 1359-6446 ISO Abbreviation: Drug Discov. Today Publication Date: 2005 Dec |
Date Detail:
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Created Date: 2005-12-26 Completed Date: 2006-08-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9604391 Medline TA: Drug Discov Today Country: England |
Other Details:
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Languages: eng Pagination: 1639-46 Citation Subset: IM |
Affiliation:
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Department of Biomaterials, Field of Tissue Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. yasuhiko@frontier.kyoto-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Delayed-Action Preparations Growth Substances Humans Hydrogels Neovascularization, Physiologic Osteogenesis Regeneration Tissue Engineering* |
| Chemical | |
Reg. No./Substance:
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0/Delayed-Action Preparations; 0/Growth Substances; 0/Hydrogels |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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