Document Detail

Significance of "ultra-early" rebleeding in subarachnoid hemorrhage.
MedLine Citation:
PMID:  3373285     Owner:  NLM     Status:  MEDLINE    
Knowledge of the local incidence of aneurysm rupture permits the conclusion that almost every patient in the population of 933,800 persons served by the authors' institution who was stricken by this catastrophe and survived long enough to be transported was treated at this center (121 patients during 34 months). Of these, 9.1% were admitted late (greater than 72 hours after subarachnoid hemorrhage (SAH]; of the remaining cases, 94.5% were seen within 24 hours and 50% within 6 hours post-SAH. Of the 121 patients, 10% were neurologically devastated on arrival, a late operation was planned for 19%, and the earliest possible surgery and nimodipine administration was selected for 71%. In this latter group, 50% of the operations were begun within 24 hours and 76% within 48 hours post-SAH. Sixty percent of all mortality and morbidity could be linked to the initial aneurysm bleed. The remaining 40% could be ascribed to potentially avoidable causes of unfavorable outcome. No less than 9.6% of all patients admitted within 24 hours after SAH suffered from "ultra-early" rebleeding during transportation or preparation for operation. The mortality rate from such rebleeding was 7.4%, compared with the 9.1% combined mortality rate from complications and late ischemia.
J Hillman; C von Essen; W Leszniewski; I Johansson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  68     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-06-24     Completed Date:  1988-06-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  901-7     Citation Subset:  AIM; IM    
Department of Surgery, University Hospital, Linköping, Sweden.
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MeSH Terms
Hematoma / drug therapy,  surgery
Intracranial Aneurysm / complications
Mental Disorders / etiology
Middle Aged
Nervous System Diseases / etiology
Nimodipine / therapeutic use
Rupture, Spontaneous
Subarachnoid Hemorrhage / complications,  drug therapy,  physiopathology*,  surgery
Time Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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