Document Detail

Significance of post-exercise increment of urinary bicarbonate and pH in subjects loaded with submaximal cycling exercise.
MedLine Citation:
PMID:  15065646     Owner:  NLM     Status:  MEDLINE    
We studied the changes in urinary bicarbonate, urinary pH and some physical parameters such as minute ventilation (VE), oxygen consumption (VO2), respiratory carbon dioxide (VCO2), heart rate, blood pressure, and blood lactate, before and after the submaximal exercise. Six male subjects aged 28-33 years were involved in the study. They performed the incremental exercise test using a bicycle ergometer until exhaustion. Levels of VE, VO2, VCO2, heart rate, and blood pressure increased continuously with an increase in cycling intensity. These parameters markedly decreased and reached the baseline levels within 5-10 minutes after the termination of exercise. According to an increase in cycling intensity, blood lactate increased continuously during exercise, but after termination of exercise the return of lactate to the baseline level was markedly retarded. Urinary bicarbonate and pH were within the range of those at 0 time (baseline levels) from the beginning until 30 minutes after the exercise. However, they began to increase abruptly about 30 minutes after the exercise, and continued to increase extensively for 2 hours thereafter. Such marked increase in urinary bicarbonate and pH seemed to be correlated with the aerobic metabolism of lactate in the muscles, liver, and kidney, finally producing CO2. It was also suggested that the measurement of urinary bicarbonate and pH may be useful for the estimation of physiological changes in the body after submaximal incremental cycling exercise loading.
Tetsushi Moriguchi; Akio Tomoda; Shiro Ichimura; Yuko Odagiri; Shigeru Inoue; Takeshi Nagasawa; Hiroshi Tanaka; Naoki Nakagawa; Teruichi Shimomitsu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  202     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-04-06     Completed Date:  2004-10-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  203-11     Citation Subset:  IM    
Department of Preventive Medicine and Public Health, Tokyo Medical University, Tokyo 160-8402, Japan.
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MeSH Terms
Bicarbonates / urine*
Carbon Dioxide / metabolism
Exercise Test*
Hydrogen-Ion Concentration*
Lactic Acid / blood
Urine / chemistry*
Reg. No./Substance:
0/Bicarbonates; 124-38-9/Carbon Dioxide; 50-21-5/Lactic Acid

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