| Significance of limb trauma as an initiating factor in chronic leg ulceration. | |
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MedLine Citation:
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PMID: 18467622 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To assess differences in clinical outcomes between patients with traumatic and spontaneous leg ulcers. METHODS: Consecutive leg ulcer follow-up patients seen between April 2004 and October 2005 in a specialist leg ulcer clinic were asked about the mechanism of the original ulceration. Twenty-four-week healing and 12-month recurrence rates were calculated using Kaplan-Meier analysis and outcomes were compared between groups with traumatic and spontaneous ulcers. RESULTS: Of the 300 patients assessed, 38 were excluded (incomplete data). In the remaining 262 patients, cause of ulceration was traumatic in 116/262 (44%) and spontaneous in 146/262 (56%). Age, ankle brachial pressure index <0.85 and venous reflux were equally distributed between groups with traumatic and spontaneous ulcers (P = 0.470, 0.793, 0.965 respectively, Chi-square test). Twenty-four-week healing rates were 81% for traumatic and 67% for spontaneous ulcers (P = 0.015, Log-Rank test). Twelve-month recurrence rates were 32% for traumatic and 33% for spontaneous ulcers (P = 0.970, Log-rank test). Patients with traumatic ulcers suffered a total of 53 ulcer recurrences (median 0, range 0-4) compared with 89 in patients with spontaneous ulcers (median 0, range 0-8) (P < 0.001, Mann-Whitney U test). CONCLUSION: Approximately half of all leg ulcer patients recall a traumatic event. When managed in leg ulcer clinic, traumatic ulcers heal faster and recur less frequently than spontaneous ulcers. |
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Authors:
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S R Kulkarni; M S Gohel; M R Whyman; K R Poskitt |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Phlebology / Venous Forum of the Royal Society of Medicine Volume: 23 ISSN: 0268-3555 ISO Abbreviation: Phlebology Publication Date: 2008 |
Date Detail:
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Created Date: 2008-05-09 Completed Date: 2008-08-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9012921 Medline TA: Phlebology Country: England |
Other Details:
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Languages: eng Pagination: 130-6 Citation Subset: IM |
Affiliation:
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Department of Vascular Surgery, Cheltenham General Hospital, Sandford Road, Cheltenham, Gloucestershire GL53 7AN, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Chronic Disease Female Humans Kaplan-Meiers Estimate Leg Injuries / complications*, epidemiology, physiopathology* Leg Ulcer / epidemiology, etiology*, physiopathology* Male Middle Aged Recurrence Risk Factors Wound Healing* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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