Document Detail


Significance of PET/CT in determining actual TNM staging for patients with various lung cancers.
MedLine Citation:
PMID:  21066996     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We investigated the difference in TNM stage of lung cancer provided by PET/CT (combining positron emission tomography and computed tomography) as compared with TNM stage obtained with conventional imaging studies (CI) with contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI) with iron contrast media. Sixty-seven cases of lung cancer were included in this study. Overall, the rate of correction of TNM staging was 70.1% after PET/CT. The correction rate for each factor was 32.8% in T, 37.3% in N, and 37.3% in M. High rates of correction were observed in small cell lung cancer (SCLC), with 75% (6/8 cases) obtained by PET/CT. When SCLCs were divided into limited disease (n = 6) involving 1 hemithorax, including mediastinal and contralateral hilar lymph nodes, and others (extensive disease, n = 2), the correction rate was as high as 80% for limited disease. In conclusion, PET/CT can provide actual TNM staging and recognition for oncologists in staging, which would not mislead to selection of inadequate subsequent treatment.
Authors:
Kenya Chiba; Midori Isoda; Masako Chiba; Takashi Kanematsu; Susumu Eguchi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International surgery     Volume:  95     ISSN:  0020-8868     ISO Abbreviation:  Int Surg     Publication Date:    2010 Jul-Sep
Date Detail:
Created Date:  2010-11-11     Completed Date:  2010-12-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0043524     Medline TA:  Int Surg     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  197-204     Citation Subset:  IM    
Affiliation:
Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / pathology,  radiography
Aged
Carcinoma, Squamous Cell / pathology,  radiography
Diagnostic Errors / prevention & control
Female
Humans
Lung Neoplasms / pathology*,  radiography
Lymphatic Metastasis
Male
Neoplasm Staging / methods*,  standards
Positron-Emission Tomography
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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