| Signet ring cell carcinoma of prostate. Immunohistochemical and ultrastructural study of a case. | |
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MedLine Citation:
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PMID: 2476883 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Signet ring cell adenocarcinoma (SRCA) is an extremely rare tumor of the prostate. We document with histochemistry, immunohistochemistry, and electron microscopy an incidental "signet ring" cell adenocarcinoma of the prostate in a fifty-seven-year-old white male with chronic lymphocytic leukemia who died of an intracerebral hemorrhage. The signet ring cells stained weakly for neutral mucin and were strongly positive for both prostate-specific antigen and prostate acid phosphatase. In addition, electron microscopy demonstrated intracellular lumina with microvilli and cytoplasmic vacuoles of mucin. This case conclusively supports the existence of SRCA of the prostate. |
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Authors:
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A G Hejka; D M England |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Urology Volume: 34 ISSN: 0090-4295 ISO Abbreviation: Urology Publication Date: 1989 Sep |
Date Detail:
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Created Date: 1989-10-13 Completed Date: 1989-10-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0366151 Medline TA: Urology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 155-8 Citation Subset: IM |
Affiliation:
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Department of Pathology, Middleton Memorial Veterans Hospital, Madison, Wisconsin. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acid Phosphatase
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analysis Adenocarcinoma, Mucinous* / metabolism, ultrastructure Antigens, Neoplasm / analysis Humans Immunoenzyme Techniques Male Microscopy, Electron Middle Aged Mucins / analysis Prostate / ultrastructure* Prostate-Specific Antigen Prostatic Neoplasms* / metabolism, ultrastructure Tumor Markers, Biological / analysis |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Neoplasm; 0/Mucins; 0/Tumor Markers, Biological; EC 3.1.3.2/Acid Phosphatase; EC 3.4.21.77/Prostate-Specific Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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