Document Detail

Signal-averaged P-wave abnormalities and atrial size in patients with and without idiopathic paroxysmal atrial fibrillation.
MedLine Citation:
PMID:  10740152     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The relation between abnormalities in the signal-averaged P wave and atrial size has not been determined in patients with paroxysmal atrial fibrillation (PAF) without structural heart disease. METHODS: Signal-averaged electrocardiograms of P waves were recorded in 38 patients with idiopathic PAF and 34 control subjects. Filtered P-wave duration (FPD) and root-mean-square voltages for the last 20 ms of the vector magnitude were measured. Atrial volume was calculated by cine magnetic resonance imaging. RESULTS: FPD was longer (131.7 +/- 10.9 ms vs 120.8 +/- 8.6 ms, P <.0001) and root-mean-square voltage was lower (2.89 +/- 1.29 microV vs 3.62 +/- 1.48 microV, P <.05) in the PAF group than in control subjects. However, the various atrial volumes were similar in the 2 groups. In controls, FPD was significantly correlated with left (r = 0.593, P <.0001) and total (r = 0.492, P <.005) atrial volume but not with right atrial volume. In patients with PAF, no significant correlations were found between FPD and any of the atrial volumes. Elderly patients with PAF (age > or =60 years) showed longer FPD than younger patients with PAF (139.2 +/- 9.4 ms vs 125.6 +/- 8.0 ms, P <.0001). CONCLUSIONS: FPD is influenced by the left and total atrial volumes in the normal heart without PAF. Prolonged FPD seems to be a useful predictor of idiopathic PAF among patients without atrial enlargement, especially in the elderly.
N Ishimoto; M Ito; M Kinoshita
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  139     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-06-01     Completed Date:  2000-06-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  684-9     Citation Subset:  AIM; IM    
First Department of Internal Medicine, Shiga University of Medical Science, Japan.
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MeSH Terms
Atrial Fibrillation / diagnosis*,  physiopathology
Atrial Function / physiology*
Cardiac Volume / physiology
Electrocardiography / instrumentation*
Heart Failure / diagnosis,  physiopathology
Magnetic Resonance Imaging, Cine
Middle Aged
Reference Values
Signal Processing, Computer-Assisted / instrumentation*
Tachycardia, Paroxysmal / diagnosis*,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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