Document Detail

Sign of Leser-Trélat associated with adenocarcinoma of the rectum.
MedLine Citation:
PMID:  11358736     Owner:  NLM     Status:  MEDLINE    
The acute onset and/or rapid increase in size and number of multiple seborrheic keratoses associated with internal malignancy is called sign of Leser-Trélat. Although some authors reject its existence, there are more than 80 well-documented case reports in the literature. Here, we report a 75-year-old man who presented with abrupt appearance of multiple seborrheic keratoses without any suspicious symptom of cancer. The screening for malignant neoplasms let us detect a rectal adenocarcinoma that was in a curative stage. This case-report illustrates a true sign of Leser-Trélat, and proves that these patients must be appropriately investigated for underlying malignancy.
M Ginarte; D Sánchez-Aguilar; J Toribio
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of dermatology : EJD     Volume:  11     ISSN:  1167-1122     ISO Abbreviation:  Eur J Dermatol     Publication Date:    2001 May-Jun
Date Detail:
Created Date:  2001-05-18     Completed Date:  2001-07-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9206420     Medline TA:  Eur J Dermatol     Country:  France    
Other Details:
Languages:  eng     Pagination:  251-3     Citation Subset:  IM    
Department of Dermatology, Complejo Hospitalario Universitario, Faculty of Medicine, Santiago de Compostela, Spain.
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MeSH Terms
Adenocarcinoma / classification,  complications*,  diagnosis
Barium Sulfate / diagnostic use
Contrast Media
Keratosis, Seborrheic / etiology*,  pathology
Mass Screening
Neoplasm Staging
Rectal Neoplasms / classification,  complications*,  diagnosis
Reg. No./Substance:
0/Contrast Media; 7727-43-7/Barium Sulfate

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