| Sideroblastic anaemia and leukaemia in multiple myeloma. | |
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MedLine Citation:
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PMID: 105698 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two patients with IgA myeloma and one patient with kappa light chain disease developed sideroblastic anaemia from two to four years after the initial diagnosis. All had previously received radiotherapy and chemotherapy (melphalan and prednisone). In two patients the myeloma was quiescent when the sideroblastic change occurred. Leukaemia occurred in two patients two and seven months respectively after the diagnosis of sideroblastic anaemia was made. In one of them, the myeloma became active again at the same time. The development of sideroblastic anaemia may be a pre-leukaemic event and may be recognised by the appearance of a dimorphic blood film. |
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Authors:
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K P Phadke; Y L Kwan; S G Young |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Australian and New Zealand journal of medicine Volume: 8 ISSN: 0004-8291 ISO Abbreviation: Aust N Z J Med Publication Date: 1978 Oct |
Date Detail:
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Created Date: 1979-04-26 Completed Date: 1979-04-26 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1264322 Medline TA: Aust N Z J Med Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 539-43 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Sideroblastic
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etiology* Female Humans Immunoglobulin A Immunoglobulin kappa-Chains Leukemia / etiology* Male Melphalan / adverse effects, therapeutic use Middle Aged Multiple Myeloma / complications*, immunology, therapy Prednisone / adverse effects, therapeutic use Preleukemia |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin A; 0/Immunoglobulin kappa-Chains; 148-82-3/Melphalan; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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