Document Detail

Side effects of spiramycin masquerading as local anesthetic toxicity during labor epidural analgesia.
MedLine Citation:
PMID:  20627689     Owner:  NLM     Status:  MEDLINE    
Significant fetal bradycardia occurred when a parturient receiving labor epidural analgesia experienced generalized numbness and tingling, a metallic taste and hot flushes. An emergent cesarean delivery under general anesthesia was performed with favorable outcomes for the mother and baby. The most likely source of the maternal symptoms was spiramycin, which was being administered for treatment of toxoplasmosis.
B Julliac; H Théophile; M Begorre; B Richez; F Haramburu
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-06-03
Journal Detail:
Title:  International journal of obstetric anesthesia     Volume:  19     ISSN:  1532-3374     ISO Abbreviation:  Int J Obstet Anesth     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-08-20     Completed Date:  2010-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200430     Medline TA:  Int J Obstet Anesth     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  331-2     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Ltd. All rights reserved.
Département d'Anesthésie et Réanimation 4, CHU de Bordeaux, France.
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MeSH Terms
Analgesia, Epidural*
Analgesia, Obstetrical*
Anesthetics, Local / adverse effects*
Anti-Bacterial Agents / adverse effects*
Cesarean Section
Fetal Therapies
Labor, Obstetric
Medication Errors
Paresthesia / chemically induced,  etiology
Pregnancy Outcome
Spiramycin / adverse effects*
Tetralogy of Fallot / surgery
Young Adult
Reg. No./Substance:
0/Anesthetics, Local; 0/Anti-Bacterial Agents; 8025-81-8/Spiramycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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