Document Detail

Sickle hemoglobin and the gravid patient: a management controversy.
MedLine Citation:
PMID:  7438667     Owner:  NLM     Status:  MEDLINE    
It is evident that patients with sickle cell disease are now in an era when they can safely complete a pregnancy with a reasonable expectation of a good outcome for both the mother and baby. Although there are vast disagreements as to which techniques (both diagnostic and therapeutic) to employ, the use of individualized methods in various geographic areas will yield the best result. To conclusively answer the questions raised in this article, a large multi-center collaborative study must be performed. If randomized treatment regimens of "transfusion versus no transfusion" were carried out in such a study, the true risk of both approaches could be assessed. Moreover, with adequate follow-up studies many of the risks of each type of treatment could be evaluated. Only through such a large study will these controversies be resolved.
J C Morrison; M G Propst; P G Blake
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinics in perinatology     Volume:  7     ISSN:  0095-5108     ISO Abbreviation:  Clin Perinatol     Publication Date:  1980 Sep 
Date Detail:
Created Date:  1981-02-24     Completed Date:  1981-02-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  273-84     Citation Subset:  IM    
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MeSH Terms
Anemia, Sickle Cell / complications,  diagnosis,  therapy*
Blood Transfusion
Delivery, Obstetric
Infant Mortality
Infant, Newborn
Infant, Newborn, Diseases / therapy
Iron / therapeutic use
Mass Screening
Maternal Mortality
Pregnancy Complications, Hematologic / therapy*
Sterilization, Reproductive
Sterilization, Tubal
Reg. No./Substance:
0/Hemoglobins; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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