| Sickle cell disease: continuous arterial spin-labeling perfusion MR imaging in children. | |
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MedLine Citation:
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PMID: 12663827 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cerebral blood flow (CBF) was measured with continuous arterial spin-labeling perfusion magnetic resonance (MR) imaging in 14 children with sickle cell disease and seven control subjects. Mean CBF values were higher in patients (P <.005) than in control subjects in all cerebral artery territories. Three patients had decreased CBF in right anterior and middle cerebral artery territories compared with CBF on the left, and one patient had a profound decrease in CBF in all three territories in the right hemisphere. Baseline CBF was significantly decreased in territories seen as unaffected on conventional MR images and MR angiograms in four children with sickle cell disease. |
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Authors:
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Kader K Oguz; Xavier Golay; Francesca B Pizzini; Catherine A Freer; Nevada Winrow; Rebecca Ichord; James F Casella; Peter C M van Zijl; Elias R Melhem |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. Date: 2003-03-27 |
Journal Detail:
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Title: Radiology Volume: 227 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-05-06 Completed Date: 2003-07-08 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 567-74 Citation Subset: AIM; IM |
Copyright Information:
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Copyright RSNA, 2003 |
Affiliation:
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Dept of Radiology, Johns Hopkins Med Insts, Baltimore, Md, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Sickle Cell
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radiography* Cerebrovascular Circulation* Child Female Humans Magnetic Resonance Imaging / methods* Male |
| Grant Support | |
ID/Acronym/Agency:
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R21-0035-01//PHS HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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