Document Detail

Sickle cell crisis treated by exchange transfusion. Treatment of two patients with heterozygous sickle cell syndrome.
MedLine Citation:
PMID:  1173102     Owner:  NLM     Status:  MEDLINE    
In two patients with severe painful sickle cell crisis and a deteriorating clinical course, recovery coincided with large-scale exchange transfusions (6 liters). The one patient, with sickle cell beta thalassemia, achieved a 90% exchange, calculated on the sickle cell hemoglobin present before and after transfusion. The other patient, with sickle cell hemoglobin Hb A, S, and (Hb) C disease, also achieved an 80% exchange calculated on the level of HbA.S. AND C in samples before and after transfusion.
M Green; R J Hall; R G Huntsman; A Lawson; T C Pearson; P C Wheeler
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JAMA     Volume:  231     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1975 Mar 
Date Detail:
Created Date:  1975-07-01     Completed Date:  1975-07-01     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  948-50     Citation Subset:  AIM; IM    
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MeSH Terms
Anemia, Sickle Cell / complications,  therapy*
Bicarbonates / therapeutic use
Calcium / therapeutic use
Chlorides / therapeutic use
Exchange Transfusion, Whole Blood*
Fever / diagnosis
Hemoglobin C Disease / therapy
Sodium / therapeutic use
Tachycardia / diagnosis
Thalassemia / drug therapy,  therapy
Reg. No./Substance:
0/Bicarbonates; 0/Chlorides; 9NEZ333N27/Sodium; SY7Q814VUP/Calcium

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