| Sickle cell microRNAs inhibit the malaria parasite. | |
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MedLine Citation:
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PMID: 22901533 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Sickle cell hemoglobin conveys resistance to malaria. In this issue of Cell Host & Microbe, LaMonte et al. (2012) demonstrate a surprising mechanism for this innate immunity. A microRNA enriched in sickle red blood cells is translocated into the parasite, incorporated covalently into P. falciparum mRNAs and inhibits parasite growth. |
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Authors:
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Manoj T Duraisingh; Harvey F Lodish |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Cell host & microbe Volume: 12 ISSN: 1934-6069 ISO Abbreviation: Cell Host Microbe Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-08-20 Completed Date: 2013-01-16 Revised Date: 2013-06-06 |
Medline Journal Info:
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Nlm Unique ID: 101302316 Medline TA: Cell Host Microbe Country: United States |
Other Details:
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Languages: eng Pagination: 127-8 Citation Subset: - |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Harvard School of Public Health, Boston, MA 02115, USA. mduraisi@hsph.harvard.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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R01 DK068348/DK/NIDDK NIH HHS |
| Comments/Corrections | |
Comment On:
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Cell Host Microbe. 2012 Aug 16;12(2):187-99
[PMID:
22901539
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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