Document Detail

Shrinking spinal cord following transverse myelopathy in a patient with systemic lupus erythematosus and the phospholipid antibody syndrome.
MedLine Citation:
PMID:  9676779     Owner:  NLM     Status:  MEDLINE    
A 38-year-old woman with systemic lupus erythematosus and the phospholipid antibody syndrome was admitted because of rapidly evolving symptoms consistent with a transverse myelopathy at the TH9/10 level. Magnetic resonance imaging (MRI) showed slight diffuse swelling and increased signal intensity of the spinal cord. She was treated with high dose methylprednisolone plus azathioprine and aspirin. Four months later she had achieved almost complete remission with minimal residual sphincter disturbances. Despite the clinical recovery, repeated MRI at 4 months and 4 years showed diffuse and irreversible atrophy of the entire spinal cord.
V Schantz; L L Oestergaard; P Junker
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  25     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-09-29     Completed Date:  1998-09-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1425-8     Citation Subset:  IM    
Department of Internal Medicine C, Odense University Hospital, Denmark.
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MeSH Terms
Antiphospholipid Syndrome / complications*
Atrophy / etiology
Lupus Erythematosus, Systemic / complications*
Magnetic Resonance Imaging
Myelitis, Transverse / complications*
Spinal Cord / pathology*

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