Document Detail

Should we treat minor degrees of glucose intolerance in pregnancy?
MedLine Citation:
PMID:  9542269     Owner:  NLM     Status:  MEDLINE    
We examined the pregnancy outcome of 112 women classified as minor degrees of glucose intolerance (MDGI) in pregnancy in a screening program based on Carpenter and Coustan's criteria. The MDGI group comprised 49 women with abnormal oral glucose challenge test (OGCT) followed by normal OGTT (group A), and 63 with "borderline" OGTT (1 abnormal value, group B). No treatment was offered to 88 MDGI women, while 26 received dietary advice and metabolic monitoring. A control group was constituted from 112 age- and BMI-matched negative screenees. Similar rates of cesarean sections and macrosomia, but higher rate of large for gestational age (LGA) babies (25.9% vs 14.3%) were found in MDGI, without difference between groups A and B. When comparing treated and untreated MDGI, lower LGA incidence (11.5% vs 30.2%) and no macrosomia were found in the former. In conclusion, untreated MDGI may present excessive fetal growth, which can be normalized by dietary treatment and metabolic monitoring.
M Bonomo; M L Gandini; A Farina; E Bonfadini; M P Pisoni; A Prudenziati; E Mion; P Greco
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Annali dell'Istituto superiore di sanità     Volume:  33     ISSN:  0021-2571     ISO Abbreviation:  Ann. Ist. Super. Sanita     Publication Date:  1997  
Date Detail:
Created Date:  1998-05-21     Completed Date:  1998-05-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7502520     Medline TA:  Ann Ist Super Sanita     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  393-7     Citation Subset:  IM    
Centro di Diabetologia e Malattie Metaboliche, Ospedale Niguarda Ca' Granda, Milan, Italy.
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MeSH Terms
Glucose Intolerance / therapy*
Pregnancy Complications / therapy*
Pregnancy Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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