| Should we offer expectant management in cases of severe preterm preeclampsia with fetal growth restriction? | |
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MedLine Citation:
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PMID: 15846190 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to assess maternal and fetal morbidity and death in cases of severe preterm preeclampsia that were managed expectantly. STUDY DESIGN: It is a retrospective study that included 155 singleton pregnancies with severe preeclampsia at <34 weeks of gestation that were managed expectantly over a 10-year period. Perinatal outcomes of both mother and fetus were stratified according to gestational age and the severity of fetal growth restriction < or =3th percentile, 4th to 5th percentile, >5th to10th percentile, and >10th percentile. RESULTS: The mean gestational age at admission was 30.2 +/- 2.4 weeks (range, 23.9-34.0 weeks). The mean latency period was 5.3 +/- 5.2 days, with a perinatal mortality rate of 3.9%. Gestational age of <30 weeks of gestation was the strongest variable that affected perinatal outcome, whereas fetal growth restriction played a marginal role. CONCLUSION: Expectant management is recommended strongly in fetuses at <30 weeks of gestation, irrespective of fetal growth restriction. Delivery should be considered at >30 weeks of gestation. |
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Authors:
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Roberta M Shear; Denyse Rinfret; Line Leduc |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 192 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2005 Apr |
Date Detail:
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Created Date: 2005-04-22 Completed Date: 2005-05-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 1119-25 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, Maternal Fetal Medicine Division, Sainte-Justine Hospital, Montreal, Quebec, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Cohort Studies Combined Modality Therapy Female Fetal Death / epidemiology* Fetal Growth Retardation / therapy*, ultrasonography Gestational Age Humans Infant, Newborn Infant, Premature* Infant, Small for Gestational Age Maternal Mortality / trends* Middle Aged Pre-Eclampsia / diagnosis, therapy* Pregnancy Pregnancy Outcome* Probability Retrospective Studies Risk Assessment Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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