Document Detail

Should we offer expectant management in cases of severe preterm preeclampsia with fetal growth restriction?
MedLine Citation:
PMID:  15846190     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to assess maternal and fetal morbidity and death in cases of severe preterm preeclampsia that were managed expectantly. STUDY DESIGN: It is a retrospective study that included 155 singleton pregnancies with severe preeclampsia at <34 weeks of gestation that were managed expectantly over a 10-year period. Perinatal outcomes of both mother and fetus were stratified according to gestational age and the severity of fetal growth restriction < or =3th percentile, 4th to 5th percentile, >5th to10th percentile, and >10th percentile. RESULTS: The mean gestational age at admission was 30.2 +/- 2.4 weeks (range, 23.9-34.0 weeks). The mean latency period was 5.3 +/- 5.2 days, with a perinatal mortality rate of 3.9%. Gestational age of <30 weeks of gestation was the strongest variable that affected perinatal outcome, whereas fetal growth restriction played a marginal role. CONCLUSION: Expectant management is recommended strongly in fetuses at <30 weeks of gestation, irrespective of fetal growth restriction. Delivery should be considered at >30 weeks of gestation.
Roberta M Shear; Denyse Rinfret; Line Leduc
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  192     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-04-22     Completed Date:  2005-05-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1119-25     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Maternal Fetal Medicine Division, Sainte-Justine Hospital, Montreal, Quebec, Canada.
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MeSH Terms
Cohort Studies
Combined Modality Therapy
Fetal Death / epidemiology*
Fetal Growth Retardation / therapy*,  ultrasonography
Gestational Age
Infant, Newborn
Infant, Premature*
Infant, Small for Gestational Age
Maternal Mortality / trends*
Middle Aged
Pre-Eclampsia / diagnosis,  therapy*
Pregnancy Outcome*
Retrospective Studies
Risk Assessment
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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