Document Detail

Should pregnancy be considered a risk factor for aortic dissection? Two cases of acute aortic dissection following cesarean section in non-Marfan nor bicuspid aortic valve patients.
MedLine Citation:
PMID:  18446126     Owner:  NLM     Status:  MEDLINE    
Acute aortic dissection in pregnancy is a rare event and rarer still in healthy young women; however, women with a bicuspid aortic valve or the Marfan syndrome are at a higher risk of dissection. The relationship between pregnancy and aortic dissection is still unclear. We describe the cases of two women with no history of cardiovascular disease who developed an acute aortic type A dissection within a few days after term delivery. Surgical repair was performed with ascending aorta replacement and aortic valve sparing. In both cases, the dissection was diagnosed within a few days following cesarean section done neither because of fetal or maternal distress. To date, only one case of type A and two cases of type B aortic dissection following cesarean section have been reported. Compared with spontaneous delivery, scheduled cesarean section, as in our cases, allows for better control of hemodynamic parameters and should protect against aortic dissection. Postoperative screening for inherent connective tissue disorders detected no mutations within the fibrillin and collagen gene chromosome in either patient. Postoperative recovery was uneventful, and the patients were discharged on postoperative days 7 and 8, respectively.
G Gelpi; M Pettinari; M Lemma; A Mangini; P Vanelli; C Antona
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  49     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-04-30     Completed Date:  2008-08-26     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  389-91     Citation Subset:  IM    
Cardiovascular Division, L. Sacco Hospital, University of Milan, Milan, Italy.
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MeSH Terms
Acute Disease
Aneurysm, Dissecting / diagnosis*,  etiology,  surgery
Aortic Aneurysm, Thoracic / diagnosis*,  etiology,  surgery
Aortic Valve / abnormalities
Cesarean Section*
Marfan Syndrome / complications
Pregnancy Outcome
Puerperal Disorders / diagnosis*,  surgery
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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