Document Detail

Should ambulatory blood pressure monitoring be mandatory for future studies in resistant hypertension: a perspective.
MedLine Citation:
PMID:  22495128     Owner:  NLM     Status:  In-Data-Review    
Recent technologic advances rekindled interventional management of resistant hypertension, either by carotid baroreceptor activation or renal sympathetic denervation. Interventional techniques result in impressive falls in office blood pressure (BP); however, ambulatory BP reductions are rather modest. This disparity between office and ambulatory BP reductions is observed with antihypertensive drugs, but at a much lower degree. Available explanations are not convincing, therefore, we propose that sympathetic overactivity may partially explain this divergence. Further studies are needed to prove or disprove our hypothesis.
Michael Doumas; Panagiota Anyfanti; George Bakris
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of hypertension     Volume:  30     ISSN:  1473-5598     ISO Abbreviation:  J. Hypertens.     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  874-6     Citation Subset:  IM    
aHypertension Unit, Veterans Affairs Medical Centre, George Washington University, Washington, District of Columbia, USA bHypertension Unit, Second Prop Department of Internal Medicine, Aristotle University, Thessaloniki, Greece cHypertensive Diseases Unit, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA.
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