| Should We Treat Thalassemia-Induced Osteoporosis: Two Case Reports. | |
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MedLine Citation:
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PMID: 23032499 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We report two cases of beta-thalassemia-induced osteoporosis. A man and a woman presented an osteoporosis at the densitometry and were treated with bisphoshonate iv. All the studies analysed the efficacity of bisphosphonate, in particular zoledronate seems to be effective. Concerning the pathogenesis, the RANK-RANK-Ligand and OPG play a major role in bone-resorption and seem to be the principal implicated mecanism for the development of osteoporosis in BTM. At the moment there is no study evaluating the efficacity of denosumab in the BTM. |
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Authors:
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M Lucini; D Stoll; B Aubry-Rozier; O Lamy |
Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Praxis Volume: 101 ISSN: 1661-8157 ISO Abbreviation: Praxis (Bern 1994) Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101468093 Medline TA: Praxis (Bern 1994) Country: - |
Other Details:
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Languages: GER Pagination: 1325-1329 Citation Subset: - |
Affiliation:
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Centre de Maladie Osseuse, Département de l'Appareil Locomoteur, CHUV, Lausanne. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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