Document Detail

Should ICSI be used in non-male factor infertility?
MedLine Citation:
PMID:  15353089     Owner:  NLM     Status:  MEDLINE    
There is general agreement that intracytoplasmic sperm injection (ICSI) should be used in male factor infertility cases, such as oligoasthenoteratozoospermia, presence of anti-sperm antibodies, or azoospermia, these cases being diagnosed through abnormal semen analysis. There are no randomized clinical trials comparing ICSI with IVF (or other interventions) where semen quality is so poor that IVF would not achieve fertilization. It is accepted that ICSI is the only treatment option in those circumstances. The role of ICSI where IVF can be expected to give a reasonable fertilization rate is the question that needs to be answered. The argument is whether or not ICSI should be used for all cases of infertility. This paper proposes and strongly supports the use of ICSI for all indications. Considerations of fertilization and embryo development, cost effectiveness and safety will be clearly discussed.
Yasser Orief; Konstantinos Dafopoulos; Safaa Al-Hassani
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  9     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-08     Completed Date:  2005-03-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  348-56     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Shatby University Hospital, Alexandria University, Egypt.
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MeSH Terms
Chromosome Aberrations*
Fertilization / physiology*
Fertilization in Vitro / economics,  methods
Genetic Diseases, Inborn / epidemiology
Infertility, Male / therapy*
Semen / chemistry*
Sperm Injections, Intracytoplasmic / economics,  methods*

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