Document Detail

Should ICSI be the treatment of choice for all cases of in-vitro conception? Considerations of fertilization and embryo development, cost effectiveness and safety.
MedLine Citation:
PMID:  11726563     Owner:  NLM     Status:  MEDLINE    
There is now considerable discussion whether intracytoplasmic sperm injection (ICSI) should be used in all cases of IVF. A critical and balanced view of the current literature is presented. The difficult question is how to identify men with apparently normal semen who are likely to fail to achieve a pregnancy using IVF. In conclusion, from both the safety and scientific viewpoint, ICSI should only be used in cases where success at IVF is regarded as unlikely.
B Ola; M Afnan; K Sharif; S Papaioannou; N Hammadieh; C L Barratt
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  16     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-11-29     Completed Date:  2002-02-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  England    
Other Details:
Languages:  eng     Pagination:  2485-90     Citation Subset:  IM    
Assisted Conception Unit, Birmingham Women's Hospital, Edgbaston, Birmingham B15 T2G, UK.
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MeSH Terms
Blastocyst / physiology
Cost-Benefit Analysis*
Embryo, Mammalian / physiology*
Infertility, Male / therapy
Pregnancy Outcome
Sperm Injections, Intracytoplasmic* / adverse effects,  economics

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