Document Detail

Shoshin beriberi: an unusual complication of prolonged parenteral nutrition.
MedLine Citation:
PMID:  3080618     Owner:  NLM     Status:  MEDLINE    
After 4 weeks of total parenteral nutrition (TPN), a 12-yr-old girl exhibited an acute heart failure with high cardiac output, anuria, and severe lactic acidosis. The clinical, hemodynamic, and biological data suggested the diagnosis of shoshin beriberi which was proved by the low erythrocyte transketolase activity with elevated "TPP effect" and by the dramatic improvement of the patient after thiamin administration. Thiamin deficiency and severe neurological disorders have been described during long-term parenteral nutrition. To our knowledge, this is the first report of the cardiovascular complication of this vitamin deprivation in long-term TPN.
P La Selve; P Demolin; L Holzapfel; P L Blanc; G Teyssier; D Robert
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  JPEN. Journal of parenteral and enteral nutrition     Volume:  10     ISSN:  0148-6071     ISO Abbreviation:  JPEN J Parenter Enteral Nutr     Publication Date:    1986 Jan-Feb
Date Detail:
Created Date:  1986-03-26     Completed Date:  1986-03-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7804134     Medline TA:  JPEN J Parenter Enteral Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  102-3     Citation Subset:  IM    
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MeSH Terms
Acidosis / etiology
Beriberi / etiology*
Erythrocytes / enzymology
Heart Failure / etiology*
Lactates / metabolism
Parenteral Nutrition, Total / adverse effects*
Transketolase / blood
Reg. No./Substance:
0/Lactates; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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