Document Detail

Shoshin beriberi induced by long-term administration of diuretics: a case report.
MedLine Citation:
PMID:  25105030     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Previous studies have suggested that diuretic therapy for heart failure may lead to thiamine deficiency due to the increased urinary thiamine excretion. Herein, we present the case of a 61-year-old man with shoshin beriberi, a fulminant form of wet beriberi, induced by long-term diuretic therapy. The patient had a history of heart failure with preserved ejection fraction and was receiving furosemide and trichlormethiazide therapy. He presented with worsening exertional dyspnea and was admitted for heart failure exacerbation. His condition failed to improve even after intensive treatment. A hemodynamic evaluation with the Swan-Ganz catheter revealed high-output heart failure with low peripheral vascular resistance. Thiamine was administered for suspected shoshin beriberi; his hemodynamic status improved dramatically within the next six hours. The serum thiamine level was below the normal range; the patient was therefore diagnosed with shoshin beriberi. The common causes of thiamine deficiency were not identified. Long-term diuretic therapy with furosemide and thiazide was thought to have played a major role in the development of thiamine deficiency. This case illustrates the importance of considering wet beriberi as a possible cause of heart failure exacerbation in patients taking diuretics, even when the common thiamine deficiency causes are not identified with history-taking.
Naoki Misumida; Hisashi Umeda; Mitsunori Iwase
Publication Detail:
Type:  Journal Article     Date:  2014-07-03
Journal Detail:
Title:  Case reports in cardiology     Volume:  2014     ISSN:  2090-6404     ISO Abbreviation:  Case Rep Cardiol     Publication Date:  2014  
Date Detail:
Created Date:  2014-08-08     Completed Date:  2014-08-08     Revised Date:  2014-08-14    
Medline Journal Info:
Nlm Unique ID:  101576452     Medline TA:  Case Rep Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  878915     Citation Subset:  -    
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