| Shortening the voiding interval for men having chlamydia nucleic acid amplification tests. | |
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MedLine Citation:
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PMID: 19875829 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Male patients are assessed for a sexually transmitted infection provided a considerable length of time has elapsed since last micturition. The current availability of highly sensitive nucleic acid amplification tests (NAATs) for Chlamydia trachomatis (CT) and Neisseria gonorrhoea such as APTIMA Combo2 (AC2) led us to investigate the impact of voiding interval on the positivity of urine tests for CT. Male patients attending a genitourinary medicine clinic at high clinical risk for CT infection and known CT positives returning for treatment were included. Two first-void urine (FVU) specimens were collected: the first sample in the standard manner and the second sample was collected 20 minutes later or as soon as possible thereafter. Fifty-two CT-positive males were included in the analysis. All of the second samples were also CT positive and none were in the equivocal range. Paired t-test analysis did not show a significant difference between relative light unit readings of the first and second urine samples (P = 0.127). Even in male patients who have recently passed urine, FVU tested by AC2 can still reliably detect CT. This provides us opportunity for more flexible and effective patient management. |
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Authors:
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T Mathew; C O'Mahony; H Mallinson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of STD & AIDS Volume: 20 ISSN: 0956-4624 ISO Abbreviation: Int J STD AIDS Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-10-30 Completed Date: 2010-01-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9007917 Medline TA: Int J STD AIDS Country: England |
Other Details:
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Languages: eng Pagination: 752-3 Citation Subset: IM; X |
Affiliation:
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Department of Sexual Health, Countess of Chester Hospital NHS Foundation Trust, Liverpool Road, Chester CH2 3AF, UK. teenamathew@nhs.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chlamydia Infections
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diagnosis*,
urine Chlamydia trachomatis / genetics, isolation & purification* DNA, Bacterial / analysis Humans Male Nucleic Acid Amplification Techniques* Reagent Kits, Diagnostic Sensitivity and Specificity Specimen Handling / methods* Time Factors Urination Urine / microbiology* |
| Chemical | |
Reg. No./Substance:
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0/DNA, Bacterial; 0/Reagent Kits, Diagnostic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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