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Shortening the Duration of [(18)F]FDG PET Brain Examination for Diagnosis of Brain Glioma.
MedLine Citation:
PMID:  20680480     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE: Some patients cannot remain immobile for a long duration of 60 min, which is generally applied in the case of a 2-deoxy-2-[(18)F]fluoro-D: -glucose ([(18)F]FDG) dynamic positron emission tomography (PET) scan. We investigated the change of the parametric values when the time duration of PET data was shortened.
PROCEDURES: Eight normal subjects and four subjects with brain glioma were studied. The rate values of K (1), k (2), k (3), and K (i) parametric images were computed by changing the time duration from 20 to 60 min, and changes of those parametric values were compared.
RESULTS: The change was 20-30% and 3-5% for k (3) and K (i), respectively, when the scan time was shortened from 60 to 40 min. The ratios of normal and disease regions in k (3) and K (i) values were similar, and contrasts of those images were not changed when the scan time was shortened to 40 min.
CONCLUSIONS: These results demonstrate that the short time duration of [(18)F]FDG PET examination can provide an acceptable estimation of parametric k (3) and K (i) images.
Authors:
Toshihide Monden; Nobuyuki Kudomi; Yasuhiro Sasakawa; Yuka Yamamoto; Nobuyuki Kawai; Yoshihiro Nishiyama
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging     Volume:  13     ISSN:  1860-2002     ISO Abbreviation:  Mol Imaging Biol     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101125610     Medline TA:  Mol Imaging Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  754-8     Citation Subset:  IM    
Affiliation:
Department of Clinical Radiology, Kagawa University Hospital, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan, monden@med.kagawa-u.ac.jp.
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