Document Detail

Short-time low-temperature pasteurisation of human milk.
MedLine Citation:
PMID:  6756884     Owner:  NLM     Status:  MEDLINE    
Using the Oxford Human Milk Pasteuriser human milk was exposed to lower temperature and shorter time periods than employed in classical holder pasteurisation. Heating human milk at 62.5 degrees C for 5 min completely destroyed Escherichia coli, Staphylococcus aureus, and group B beta-haemolytic streptococci inoculated into the samples. Heating at 56.0 degrees C for 15 min destroyed over 99% of the inoculated organisms. The mean percentage remaining activity of certain antimicrobial proteins after heat treatment at 62.5 degrees C for 30 min, 62.5 degrees C for 5 min and 56 degrees C for 15 min were as follows: IgA 67, and 90%; lactoferrin 27, 59 and 91%; and lysozyme 67, 96 and 106%, respectively. These results suggest that human milk can be effectively pasteurised using less heat treatment than in classical holder pasteurisation. Lower temperature and shorter heat treatment also preserves substantially more of the activity of the antimicrobial proteins present in human milk.
M E Wills; V E Han; D A Harris; J D Baum
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Early human development     Volume:  7     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  1982 Oct 
Date Detail:
Created Date:  1983-02-14     Completed Date:  1983-02-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  71-80     Citation Subset:  IM    
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MeSH Terms
Escherichia coli / isolation & purification
Hot Temperature*
Immunoglobulin A / analysis
Lactoferrin / analysis
Milk, Human / analysis,  immunology,  microbiology*
Muramidase / analysis
Staphylococcus aureus / isolation & purification
Streptococcus agalactiae / isolation & purification
Time Factors
Reg. No./Substance:
0/Immunoglobulin A; 0/Lactoferrin; EC

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