| Short-term studies on the use of amino acids as an osmotic agent in continuous ambulatory peritoneal dialysis. | |
| | |
MedLine Citation:
|
PMID: 3315397 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
1. A 1% amino acid dialysis solution with a high concentration of the branched-chain amino acids has been compared with 1.36% glucose in short-term studies. 2. The 1% amino acid solution was as effective an agent as 1.36% glucose with respect to ultrafiltration and clearance of creatinine, urea and potassium. 3. Levels of branched-chain amino acids rose to the upper end of the normal range within 1 h and remained at this level over the entire period of the study. Total and non-essential amino acids had returned to baseline by the end of the cycle. 4. Blood glucose rose to significantly greater levels during the 1.36% glucose exchange than during the 1% amino acid exchange. There was an increase in serum insulin levels during both cycles; this was significantly greater with the 1% amino acid solution than the 1.36% glucose. 5. There was no evidence of short-term metabolic complications with the 1% amino acid solution. |
| | |
Authors:
|
T H Goodship; S Lloyd; P W McKenzie; M Earnshaw; I Smeaton; K Bartlett; M K Ward; R Wilkinson |
Related Documents
:
|
21571947 - Acute doxorubicin toxicity differentially alters cytochrome p450 expression and arachid... 3600287 - Amino acid metabolism during exercise in trained rats: the potential role of carnitine ... 4047127 - Production and purification of a peptide of fusarium tricinctum that causes conidia of ... 1251917 - Amino acid assignment to one of three blood-brain barrier amino acid carriers. 21177447 - Functional characterization of folic acid transport in the intestine of the laying hen ... 18811077 - The effect of retinoic acid on mouse mandibular molar development in vitro, using alkal... |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Clinical science (London, England : 1979) Volume: 73 ISSN: 0143-5221 ISO Abbreviation: Clin. Sci. Publication Date: 1987 Nov |
Date Detail:
|
Created Date: 1987-12-30 Completed Date: 1987-12-30 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7905731 Medline TA: Clin Sci (Lond) Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 471-8 Citation Subset: IM |
Affiliation:
|
Department of Medicine, University of Newcastle upon Tyne, U.K. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Amino Acids* / blood Blood Glucose / analysis Female Glucagon / blood Glucose Humans Insulin / blood Male Middle Aged Osmolar Concentration Peritoneal Dialysis, Continuous Ambulatory / methods* Solutions |
| Chemical | |
Reg. No./Substance:
|
0/Amino Acids; 0/Blood Glucose; 0/Solutions; 11061-68-0/Insulin; 50-99-7/Glucose; 9007-92-5/Glucagon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Material selective imaging and determination of density using the dual energy method. II. Clinical u...
Next Document: Haemodialysis-associated amyloidosis: beta 2-microglobulin alone or associated with globin chains?