Document Detail

Short-term reproducibility of cardiopulmonary measurements during exercise testing in patients with severe chronic heart failure.
MedLine Citation:
PMID:  9266779     Owner:  NLM     Status:  MEDLINE    
Eleven men with severe chronic heart failure (peak cardiac index 4.0 +/- 0.2 L/m2/min), six on a heart transplantation waiting list, were prospectively assessed. To determine reproducibility of cardiopulmonary and hemodynamic variables for clinical purposes during ramp bicycle ergometry, the patients underwent two ramp bicycle ergometer tests (3 minutes unloaded, work rate increments of 12.5 W/min) with a 1-week interval between tests. Oxygen uptake (VO2) carbon dioxide production (VCO2), and ventilation were measured breath by breath, and calculations were performed to determine gas exchange ratio, oxygen pulse, ventilatory equivalents of oxygen and carbon dioxide, and end-tidal partial pressure for oxygen and carbon dioxide. Additionally, heart rate, blood pressure, and lactate levels were assessed. Measurements were performed at submaximum work rate levels of 25 W, 50 W, and 75 W at ventilatory threshold and at peak work rate. At all measurement points, the coefficient of variation for cardiopulmonary variables was between 1.4% and 7.1% for submaximum work rate levels, between 1.2% and 4.4% at ventilatory threshold, and between 2.4% and 7.1% at peak work rate. For heart rate, blood pressure, and lactate levels, coefficient of variation was between 2.7% and 5.7% for submaximum work rate levels, between 1.4% and 6.1% at ventilatory threshold, and between 1.2% and 5.5% at peak work rate. The data suggest high reproducibility for duplicate measurements of cardiopulmonary and hemodynamic variables during ramp bicycle ergometry in patients with severe chronic heart failure. The results may be used to determine whether any variable in a single patient is significantly different from that obtained in a previous exercise test or if the change is within experimental error.
K Meyer; S Westbrook; M Schwaibold; R Hajric; K Peters; H Roskamm
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  134     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1997-09-11     Completed Date:  1997-09-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  20-6     Citation Subset:  AIM; IM    
Herz-Zentrum, Bad Krozingen, Germany.
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MeSH Terms
Anaerobic Threshold
Blood Pressure / physiology
Carbon Dioxide / blood,  metabolism
Cardiac Output / physiology
Chronic Disease
Exercise Test
Heart / physiopathology*
Heart Failure / physiopathology*
Heart Rate / physiology
Heart Transplantation
Hemodynamics / physiology
Lactates / blood
Lung / physiopathology*
Middle Aged
Oxygen / blood
Oxygen Consumption / physiology
Partial Pressure
Physical Exertion / physiology*
Prospective Studies
Pulmonary Gas Exchange / physiology
Reproducibility of Results
Respiration / physiology
Tidal Volume
Time Factors
Waiting Lists
Reg. No./Substance:
0/Lactates; 124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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