Document Detail

Short-term re-epithelialization of the alkali-burned rabbit cornea.
MedLine Citation:
PMID:  4083662     Owner:  NLM     Status:  MEDLINE    
Pfister and associates have shown that treatment with citrate solution reduces the incidence of stromal ulceration after alkali burn of the cornea. In the course of study of the effect of inhibitors of plasminogen activation on corneal re-epithelialization following alkali burns, we noted that when citrate was used in the medication, the healing process proceeded rapidly for three days; however, the denuded area became abruptly larger on the fourth day, and then resumed healing on the fifth day.
R A Moses; D N Brown
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of ophthalmology     Volume:  17     ISSN:  0003-4886     ISO Abbreviation:  Ann Ophthalmol     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1986-02-19     Completed Date:  1986-02-19     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0210137     Medline TA:  Ann Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  714-6     Citation Subset:  IM    
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MeSH Terms
6-Aminocaproic Acid / therapeutic use*
Aminocaproic Acids / therapeutic use*
Burns, Chemical / drug therapy*
Cornea / injuries*
Cyclohexanecarboxylic Acids / therapeutic use*
Drug Evaluation, Preclinical
Eye Burns / drug therapy*
Tranexamic Acid / therapeutic use*
Grant Support
Reg. No./Substance:
0/Aminocaproic Acids; 0/Cyclohexanecarboxylic Acids; 1197-18-8/Tranexamic Acid; 60-32-2/6-Aminocaproic Acid

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