Document Detail

Short-term performance of mitral valve replacement with porcine bioprosthetic valves in dogs.
MedLine Citation:
PMID:  17827884     Owner:  NLM     Status:  MEDLINE    
Porcine bioprosthetic valves cross-linked with glutaraldehyde and polyepoxy compound were newly developed for mitral valve replacement (MVR) in dogs. Five beagle dogs were performed a left thoracotomy and underwent MVR using the porcine bioprosthetic valves during cardiopulmonary bypass (CPB). A vein catheter inserted into right atrium and a vent catheter inserted into the right ventricle to drain. The hemodynamic conditions of CPB were excellent during surgery. The left atrial pressure was measured before and after MVR; there was no significant difference and it was normal. Thrombosis and the prosthetic valve regurgitation were not observed one week after MVR. Pressure half time (PHT) prolonged significantly (P<0.05) from 31.40 +/- 4.0 msec presurgery to 99.20 +/- 19.4 msec at seven days after MVR, although it indicated the normal range as the bioprosthetic valve. The symptom of the prosthetic valve failure was not observed. This study indicated that the MVR using porcine bioprosthetic valves under CPB might have been effective in dogs as a short-term evaluation.
Kazuaki Takashima; Aiko Soda; Ryou Tanaka; Yoshihisa Yamane
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The Journal of veterinary medical science / the Japanese Society of Veterinary Science     Volume:  69     ISSN:  0916-7250     ISO Abbreviation:  J. Vet. Med. Sci.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-09-10     Completed Date:  2007-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105360     Medline TA:  J Vet Med Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  793-8     Citation Subset:  IM    
Animal Clinical Research Foundation, 214-10 Yatsuya, Kurayoshi, Tottori 682-0025, Japan.
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MeSH Terms
Bioprosthesis / veterinary*
Cardiopulmonary Bypass / veterinary
Dog Diseases / surgery*
Heart Valve Prosthesis / veterinary*
Mitral Valve / surgery*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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