Document Detail


Short-term outcomes of mothers and newborn infants with comorbid psychiatric disorders and drug dependency.
MedLine Citation:
PMID:  19296287     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The aim of the present study was to determine the characteristics and short-term outcomes of mother-infant pairs with comorbid drug dependency and psychiatric disorders. METHODS: A population-based retrospective chart review was carried out of 879 drug-dependent mother and infant pairs in New South Wales (NSW) and the Australian Capital Territory (ACT) who delivered between 1 January and 31 December 2004. RESULTS: Psychiatric comorbidity (dual diagnosis, DD) was identified in 396 (45%) of the 879 drug-dependent women. DSM-IV depression (79%), followed by anxiety (20%), was most prevalent. DD women were more likely to use amphetamines (29% vs 18%, p < 0.05), less likely to use opiates (42% vs 51%, p < 0.05) and to have had no antenatal care (24% vs 8%, p < 0.05). They also had more previous pregnancies (4, range = 2-5 vs 3, range = 2-5, p < 0.05) and domestic violence (29% vs 14%, p < 0.05) was more common. DD infants were less likely to be admitted to a nursery (47% vs 55%, p < 0.05). Withdrawal scores were similar (maximum median Finnegan scores = 4 (interquartile range = 3-8) vs 10 (interquartile range = 7-12, p = 0.30) but fewer needed withdrawal medication (19% vs 27%, p < 0.05). Maternal psychotropic agents did not worsen the severity of neonatal withdrawal. CONCLUSIONS: Psychiatric comorbidity, especially depression, is common and affects almost half of drug-using mothers. Antenatal care, drug use and social outcomes are worse for DD mothers and their infants. It is recommended that all drug-using women be assessed antenatally for psychosocial disorders so that timely mental health intervention can be offered, if required.
Authors:
Ju Lee Oei; Mohamed E Abdel-Latif; Fiona Craig; Aivy Kee; Marie-Paule Austin; Kei Lui;
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Australian and New Zealand journal of psychiatry     Volume:  43     ISSN:  1440-1614     ISO Abbreviation:  Aust N Z J Psychiatry     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-19     Completed Date:  2009-07-13     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0111052     Medline TA:  Aust N Z J Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  323-31     Citation Subset:  IM    
Affiliation:
Department of Newborn Care, Royal Hospital for Women, NSW, Australia. ju.oei@sesiahs.health.nsw.gov.au
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MeSH Terms
Descriptor/Qualifier:
Amphetamines* / adverse effects
Comorbidity
Diagnostic and Statistical Manual of Mental Disorders
Domestic Violence / statistics & numerical data
Female
Humans
Infant, Newborn
Maternal Health Services / utilization
Mental Disorders / drug therapy*,  epidemiology*
Mothers*
Pregnancy
Prenatal Exposure Delayed Effects / epidemiology,  etiology*
Psychotropic Drugs / therapeutic use
Severity of Illness Index
Substance Withdrawal Syndrome / etiology*,  prevention & control*
Substance-Related Disorders / drug therapy,  epidemiology*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Amphetamines; 0/Psychotropic Drugs
Investigator
Investigator/Affiliation:
Adam Buckmaster / ; Adam Winstock / ; Anthony Galloway / ; Belinda Bones Saunders / ; Beth Burton / ; Bob Fonseca / ; Brendan McCorry / ; Bridgett Scott / ; Catherine Maher / ; Cheryl Laidlaw / ; Christine Stephens / ; Deborah Arthur / ; Di Diebert / ; Fiona Cooke / ; Gail Saul / ; Geoff Hardacre / ; Geoff Jacket / ; Graham Reynolds / ; Ian M R Wright / ; Inga Heyman / ; Janet Falconer / ; Jenny Stonestreet / ; John Leary / ; Jon Currie / ; Jonathan Morris / ; Joy Dickinson / ; Julianne Arundale / ; Ken Curry / ; Kim Smith / ; Linda Fawcett / ; Mark Tracy / ; Melissa Toms / ; Miriam Dayhew / ; Patricia Lutz / ; Paul Haber / ; Peter Kristidis / ; Rajiv K Agrawal / ; Ruth Jobson / ; Samar Zakaria / ; Sarah Clews / ; Susanne Wooderson / ; Sweemee Levsen / ; Tracey Halliday /

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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