| Short-term outcomes following intrauterine transfusion in Scotland. | |
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MedLine Citation:
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PMID: 19395394 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To describe neonatal outcomes following intrauterine transfusion (IUT) for severe Rhesus isoimmunisation from 1993 to 2004. RESULTS: 116 neonates who had undergone 457 IUTs (median 4, range 1-9) were identified. Three neonates died, all before 1995 (two because of hypoxic ischaemic multiorgan failure and one because of overwhelming Escherichia coli sepsis). 13 neonates (11%) were delivered by emergency Caesarean section following either IUT complication or spontaneous onset of preterm labour. They were more likely to require intubation (p<0.0001), on-going respiratory support (p=0.0007) and an exchange transfusion (p=0.007). 23 (20%) required an exchange transfusion and 63 (54%) at least one top-up transfusion. CONCLUSIONS: Management of severe Rhesus disease is associated with encouraging neonatal outcomes and most infants can be managed with phototherapy and a few top-up transfusions. IUT complications are rare but significantly increase neonatal mortality and morbidity. Antenatal counselling should address the likely postnatal course for these infants. |
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Authors:
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Laura McGlone; J H Simpson; C Scott-Lang; A D Cameron; J Brennand |
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Publication Detail:
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Type: Journal Article Date: 2009-04-23 |
Journal Detail:
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Title: Archives of disease in childhood. Fetal and neonatal edition Volume: 96 ISSN: 1468-2052 ISO Abbreviation: Arch. Dis. Child. Fetal Neonatal Ed. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-23 Completed Date: 2011-01-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9501297 Medline TA: Arch Dis Child Fetal Neonatal Ed Country: England |
Other Details:
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Languages: eng Pagination: F69-70 Citation Subset: AIM; IM |
Affiliation:
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Queen Mother's Hospital, Dalnair Street, Glasgow, Scotland, UK. lauramcglone@doctors.org.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Transfusion, Intrauterine*
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adverse effects Cesarean Section Emergencies Exchange Transfusion, Whole Blood Female Gestational Age Humans Infant, Newborn Perinatal Care / methods Phototherapy Pregnancy Pregnancy Outcome Prognosis Retrospective Studies Rh Isoimmunization / therapy* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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