Document Detail


Short-term outcome predictors in infants born at 23-24 gestational weeks.
MedLine Citation:
PMID:  18394098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: Outcome is uncertain in infants born at 23-24 gestational weeks. The aim of the present study was to identify possible early predictors of outcome in these infants. MATERIALS AND METHODS: Data from the Swedish medical birth register (MBR) for live-born infants with gestational ages (GAs) 23 and 24 weeks, born during the time-period 2000-2002, were analysed in relation to short-term outcomes, that is survival and survival without severe brain damage (intraventricular haemorrhage [IVH] grades 3 and 4 and/or periventricular leukomalacia [PVL]). RESULTS: In 57 infants born at 23 gestational weeks, survival was associated with birthweight (BW) (p = 0.018) and 5-min Apgar score (p = 0.020) on univariate analyses. In 99 infants born at 24 weeks of gestation, survival without severe brain damage correlated with BW (p = 0.039), birth type (singleton/multiple) (p = 0.017) and Apgar score at 1, 5 and 10 min (p = 0.028, 0.014 and 0.030, respectively). The best model for predicting survival without severe brain damage in infants born at 24 gestational weeks was based on 5-min Apgar score and birth type. The small number of live-born infants at 23 weeks of gestation did not allow for multiple logistic regression analyses. CONCLUSION: The 5-min Apgar score is associated with short-term outcome in live-born infants at 23-24 gestational weeks. The association is stronger for infants born at 24 weeks of gestation.
Authors:
Kristina Forsblad; Karin Källén; Karel Marsál; Lena Hellström-Westas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  97     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-08     Completed Date:  2008-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  551-6     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, Helsingborg Hospital, Helsingborg, Sweden. kristina.forsblad@telia.com
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MeSH Terms
Descriptor/Qualifier:
Apgar Score*
Female
Gestational Age*
Humans
Infant Mortality*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / etiology*
Intracranial Hemorrhages / etiology*
Male
Predictive Value of Tests
Prognosis
Registries
Survival Analysis
Sweden

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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