| Short-term outcome predictors in infants born at 23-24 gestational weeks. | |
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MedLine Citation:
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PMID: 18394098 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: Outcome is uncertain in infants born at 23-24 gestational weeks. The aim of the present study was to identify possible early predictors of outcome in these infants. MATERIALS AND METHODS: Data from the Swedish medical birth register (MBR) for live-born infants with gestational ages (GAs) 23 and 24 weeks, born during the time-period 2000-2002, were analysed in relation to short-term outcomes, that is survival and survival without severe brain damage (intraventricular haemorrhage [IVH] grades 3 and 4 and/or periventricular leukomalacia [PVL]). RESULTS: In 57 infants born at 23 gestational weeks, survival was associated with birthweight (BW) (p = 0.018) and 5-min Apgar score (p = 0.020) on univariate analyses. In 99 infants born at 24 weeks of gestation, survival without severe brain damage correlated with BW (p = 0.039), birth type (singleton/multiple) (p = 0.017) and Apgar score at 1, 5 and 10 min (p = 0.028, 0.014 and 0.030, respectively). The best model for predicting survival without severe brain damage in infants born at 24 gestational weeks was based on 5-min Apgar score and birth type. The small number of live-born infants at 23 weeks of gestation did not allow for multiple logistic regression analyses. CONCLUSION: The 5-min Apgar score is associated with short-term outcome in live-born infants at 23-24 gestational weeks. The association is stronger for infants born at 24 weeks of gestation. |
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Authors:
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Kristina Forsblad; Karin Källén; Karel Marsál; Lena Hellström-Westas |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: 97 ISSN: 0803-5253 ISO Abbreviation: Acta Paediatr. Publication Date: 2008 May |
Date Detail:
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Created Date: 2008-04-08 Completed Date: 2008-08-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: Norway |
Other Details:
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Languages: eng Pagination: 551-6 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, Helsingborg Hospital, Helsingborg, Sweden. kristina.forsblad@telia.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Apgar Score* Female Gestational Age* Humans Infant Mortality* Infant, Newborn Infant, Premature Infant, Premature, Diseases / etiology* Intracranial Hemorrhages / etiology* Male Predictive Value of Tests Prognosis Registries Survival Analysis Sweden |
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