Document Detail


Short-term effects of two integrated, non-pharmacological body weight reduction programs on coronary heart disease risk factors in young obese patients.
MedLine Citation:
PMID:  14768777     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to evaluate the short-term effects (3 weeks) on selected coronary heart disease (CHD) risk factors, 90 obese in-patients (body mass index, BMI, > or = 35 kg/m2 received a same low-calorie diet (1200-1800 kcal/day), nutritional education and psychological counselling, and were randomly assigned to either a non-specific, high-volume, low-intensity exercise training program (NET), or to an individualised, low-volume and high-intensity exercise training program (IET), for 5 days/week for 3 weeks. NET and IET programs lead to a significant reduction in blood glucose (6.2 and 7.7% respectively), total cholesterol (17.3%, 12.3%), HDL-cholesterol (13.7%, 15.2%), systolic (8.9%, 5.3%) and diastolic resting blood pressure (10.6%, 3.3%). Total CHD scores were also significantly improved (38.1%, 33.1%). The changes occurred with a relatively moderate decrease in body weight (4.2%, 4.4%) and with still elevated BMI values (41.6 kg/m2). Although IET, compared to NET program, induced smaller reductions of blood pressure, it requires 30% daily training period and may possibly enhance long-term patient compliance.
Authors:
A Sartorio; C L Lafortuna; P G Marinone; A Tavani; C La Vecchia; C Bosetti
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Diabetes, nutrition & metabolism     Volume:  16     ISSN:  0394-3402     ISO Abbreviation:  Diabetes Nutr. Metab.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2004-02-10     Completed Date:  2004-05-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8813443     Medline TA:  Diabetes Nutr Metab     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  262-5     Citation Subset:  IM    
Affiliation:
Laboratory for Experimental Endocrinology, Italian Institute for Auxology, IRCCS, Milan, Italy. sartorio@auxologico.it
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Blood Glucose / analysis
Blood Pressure
Body Mass Index
Cholesterol / blood
Cholesterol, HDL / blood
Coronary Disease / etiology,  prevention & control*
Energy Intake
Energy Metabolism
Exercise*
Female
Humans
Male
Middle Aged
Nutritional Physiological Phenomena
Obesity / complications,  therapy*
Patient Education as Topic
Risk Factors
Weight Loss*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Cholesterol, HDL; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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