| Short-term effects of atenolol in patients with dilated cardiomyopathy. | |
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MedLine Citation:
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PMID: 9623012 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dilated cardiomyopathy is a common cause of heart failure with systolic dysfunction. Medications used to treat this condition are usually for symptomatic relief. We studied the effect of atenolol in heart failure caused by dilated cardiomyopathy in a double blinded randomized fashion. There were 17 males and 5 females. All patients underwent right and left heart catheterization, coronary angiography, endomyocardial biopsy, exercise testing and doppler echocardiography. By 3 months, atenolol significantly reduced resting and exercise heart rate and pulmonary capillary wedge pressure. There was no difference in exercise capacity. We conclude from this study that atenolol improve hemodynamic condition in patients with dilated cardiomyopathy without improving exercise capacity during this short observation period. |
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Authors:
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R Krittayaphong; N Mahanonda; C Kangkagate; R Phankingthongkum; S Chaithiraphan |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the Medical Association of Thailand = Chotmaihet thangphaet Volume: 81 ISSN: 0125-2208 ISO Abbreviation: J Med Assoc Thai Publication Date: 1998 Mar |
Date Detail:
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Created Date: 1998-07-30 Completed Date: 1998-07-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7507216 Medline TA: J Med Assoc Thai Country: THAILAND |
Other Details:
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Languages: eng Pagination: 201-7 Citation Subset: IM |
Affiliation:
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Her Majesty's Cardiac Center, Bangkok, Thailand. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use* Adult Atenolol / therapeutic use* Cardiomyopathy, Dilated / drug therapy*, physiopathology Chi-Square Distribution Double-Blind Method Echocardiography Exercise Test Female Hemodynamics Humans Male Middle Aged Pulmonary Wedge Pressure / drug effects* |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 29122-68-7/Atenolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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