Document Detail


Short-term effect of prebiotics administration on stool characteristics and serum cytokines dynamics in very young children with acute diarrhea.
MedLine Citation:
PMID:  22254048     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We investigated the effect of a mixture of long-chain fructo-oligosaccharides, galacto-oligosaccharides and acidic oligosaccharides on the number and consistency of stools and on immune system biomarkers in 104 supplemented and non-supplemented subjects (aged 9-24 months) with acute diarrhea. Interleukin-1 (IL-1), IL-1RA, IL-6, IL-8, IL-10, TNF-α and sIL-2R cytokine levels were determined. The significant decrease in number of stools and increase in stool consistency in the supplemented group was of little clinical relevance. The only significant change in pro- and anti-inflammatory cytokines was decreased TNF-α levels in the supplemented group. Prebiotic supplementation during acute diarrhea episodes did not influence the clinical course.
Authors:
Nachum Vaisman; Josef Press; Eugene Leibovitz; Güenther Boehm; Vivian Barak
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Publication Detail:
Type:  Journal Article     Date:  2010-06-30
Journal Detail:
Title:  Nutrients     Volume:  2     ISSN:  2072-6643     ISO Abbreviation:  Nutrients     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2012-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101521595     Medline TA:  Nutrients     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  683-92     Citation Subset:  -    
Affiliation:
Unit of Clinical Nutrition, Tel Aviv Sourasky Medical Center, Sackler Faulty of Medicine, Tel Aviv University, Tel Aviv, 64239, Israel.
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