| Short-term effect of partially hydrolyzed formula on the prevention of development of atopic dermatitis in infants at high risk. | |
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MedLine Citation:
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PMID: 12923332 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This short-term, prospective study was aimed to assess the effects of partially hydrolyzed formula (PHF) on the prevention of the development of atopic dermatitis in infants at high risk. The infants of parents with allergy symptoms and serum total IgE over 200 kU/L were divided into 3 groups by their feeding patterns: PHF group (n=15), standard formula (SF) group (n=32), and breast milk (BM) group (n=22). No allergenic food was given during the study period of 6 months, and breastfeeding mothers avoided egg ingestion. Their atopic symptoms were monitored every 2 months. The cumulative incidence and prevalence of atopic dermatitis at the age of 6 months were significantly less in the PHF group than in the SF group (47% vs. 78%, p<0.05; 20% vs. 59%, p<0.05). Those rates of the PHF group were also less than those of the BM group, but they were not statistically significant. There was no difference in the onset age and disease severity. These results suggest that early feeding of PHF to infants at high risk has a short-term preventive effect on the development of atopic dermatitis during the first 6 months of life. Long-term preventive effects should be evaluated. |
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Authors:
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Young-Shin Han; Hwa-Young Park; Kang-Mo Ahn; Ju-Seok Lee; Hay-Mie Choi; Sang-Il Lee |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of Korean medical science Volume: 18 ISSN: 1011-8934 ISO Abbreviation: J. Korean Med. Sci. Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-08-18 Completed Date: 2004-04-30 Revised Date: 2011-03-16 |
Medline Journal Info:
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Nlm Unique ID: 8703518 Medline TA: J Korean Med Sci Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 547-51 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Breast Feeding Dermatitis, Atopic / etiology*, prevention & control* Electrophoresis, Polyacrylamide Gel Female Food Hypersensitivity Humans Hydrolysis Hypersensitivity Immunoglobulin E / blood Infant Infant Food* Infant, Newborn Male Milk, Human Prospective Studies Protein Hydrolysates / therapeutic use* Risk Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Protein Hydrolysates; 37341-29-0/Immunoglobulin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Korean Med Sci Journal ID (pmc): jkms ISSN: 1011-8934 ISSN: 1598-6357 Publisher: Korean Academy of Medical Sciences |
Article Information Download PDF  Print publication date: Month: 8 Year: 2003 Volume: 18 Issue: 4 First Page: 547 Last Page: 551 ID: 3055093 PubMed Id: 12923332 Publisher Item Identifier: 200308547 |
| Short-term effect of partially hydrolyzed formula on the prevention of development of atopic dermatitis in infants at high risk. | |
| Young-Shin Han | |
| Hwa-Young Park | |
| Kang-Mo Ahn | |
| Ju-Seok Lee | |
| Hay-Mie Choi | |
| Sang-Il Lee | |
| Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. |
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