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Short-term Effects of Air Pollution on Pulse Pressure Among Nonsmoking Adults.
MedLine Citation:
PMID:  22249240     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Previous studies on the effects of acute air pollution have focused primarily on blood pressure (BP). METHODS: Our study enrolled 9238 nonsmoking adults over 30 years of age from 6 townships in Taiwan: 1 seaport, 1 urban, 1 industrial, and 3 rural. Using generalized additive models, we evaluated the associations between brachial BP and short-term exposure to 5 air pollutants: particulate matter with diameter <10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3). RESULTS: After adjusting for individual and meteorologic factors, the systolic BP was decreased by all 5 pollutants, whereas the diastolic BP was increased by SO2, NO2, and O3. The pulse pressure was consistently decreased by all 5 pollutants, with changes of -1.5 (95% confidence interval = -2.0 to -1.1), -0.6 (-0.9 to -0.4), -2.4 (-3.0 to -1.8), -1.2 (-1.6 to -0.9), and -1.4 (-1.8 to -0.9) mm Hg for interquartile range increases in 3-day lagged PM10, SO2, NO2, carbon monoxide, and O3, respectively. PM10 exposure was more strongly associated with reduction of pulse pressure among men, persons >60 years of age, those with hypertension, and those living in the industrial township. CONCLUSIONS: Short-term exposure to air pollution reduces pulse pressure. PM10 in industrial emissions may contribute to pulse pressure changes. Age, sex, and hypertensive status may modify the effects of PM10 on pulse pressure.
Authors:
Szu-Ying Chen; Ta-Chen Su; Yu-Lun Lin; Chang-Chuan Chan
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-16
Journal Detail:
Title:  Epidemiology (Cambridge, Mass.)     Volume:  -     ISSN:  1531-5487     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9009644     Medline TA:  Epidemiology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the aDivision of Surgical Intensive Care, Department of Critical Care Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan; bInstitute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan; and cDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
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