Document Detail

Short segment Hirschsprung's disease as a cause of discrepancy between histologic, histochemical, and clinical features.
MedLine Citation:
PMID:  6854497     Owner:  NLM     Status:  MEDLINE    
Diagnostic difficulty may be encountered in Hirschsprung's disease when discrepancy is noted between the histochemical pattern, the presence or absence of ganglion cells, and clinical features. This is mainly a problem in neonates, and the cause of the discrepancy is probably due to biopsy specimens being taken above a short aganglionic segment. When short segment Hirschsprung's disease is suspected, a low suction biopsy should be taken for the demonstration of acetylcholinesterase activity.
C W Chow; P E Campbell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  18     ISSN:  0022-3468     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  167-71     Citation Subset:  IM    
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MeSH Terms
Acetylcholinesterase / metabolism
Child, Preschool
Cholinergic Fibers / pathology
Hirschsprung Disease / diagnosis*,  enzymology,  pathology
Infant, Newborn
Rectum / enzymology,  innervation,  pathology
Reg. No./Substance:

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