| Short report: analysis of anti-malaria immune response during human immunodeficiency virus infection in adults in Kinshasa, Democratic Republic of the Congo. | |
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MedLine Citation:
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PMID: 12685648 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Co-infection of human immunodeficiency virus and malaria is not uncommon in people living in sub-Saharan Africa. Since HIV infection results in immune deficiency, it may alter the ability of HIV patients to mount proper immune responses against malaria parasites. We measured specific malaria antibodies in 47 specimens from 25 couples from Kinshasa, Democratic Republic of the Congo (DRC), according to their HIV status, and investigated probable interaction between malaria and HIV infection. Plasma samples were analyzed for HIV markers (western blot and viral load) and malaria parasite-specific antibody (antibody titer, pattern of antigen recognized by western blotting, and parasite neutralizing antibodies assayed by growth inhibition). No correlation was identified between measured HIV infection status and malaria-specific parameters. |
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Authors:
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M Kashamuka; N Nzila; L Mussey; N Lubaki; T C Quinn; R Bollinger; N Kumar |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 68 ISSN: 0002-9637 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-04-10 Completed Date: 2003-05-01 Revised Date: 2008-08-20 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: United States |
Other Details:
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Languages: eng Pagination: 376-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Animals Antibodies, Protozoan / blood Democratic Republic of the Congo Female HIV Infections / complications, immunology* Humans Malaria, Falciparum / complications, immunology* Male Neutralization Tests Plasmodium falciparum / growth & development, immunology |
| Grant Support | |
ID/Acronym/Agency:
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2-D 43 TW000010-AITRP/TW/FIC NIH HHS; R03 AI45119/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Protozoan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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