Document Detail

Short- and long-term survival of patients with metastatic solid cancer admitted to the intensive care unit: prognostic factors.
MedLine Citation:
PMID:  19709168     Owner:  NLM     Status:  MEDLINE    
Decisions for intensive care unit (ICU) admissions in patients with advanced cancer are complex, and the knowledge of survival rates and prognostic factors are essential to these decisions. Ours objectives were to describe the short- and long-term survival of patients with metastatic solid cancer admitted to an ICU due to emergencies and to study the prognostic factors presented at ICU admission that could be associated with hospital mortality. We retrospectively analysed the charts of all patients with metastatic solid cancer admitted over a 1-year period. This gave a study sample of 83 patients. The ICU, hospital, 1-year and 2-year survival rates were 55.4%, 28.9%, 12.0% and 2.4% respectively. Thrombocytopenia (odds ratio 26.2; P = 0.006) and simplified acute physiology score (SAPS II) (odds ratio 1.09; P = 0.026) were independent factors associated with higher hospital mortality. In conclusion, the survival rates of patients with metastatic solid cancer admitted to the ICU due to emergencies were low, but of the same magnitude as other groups of cancer patients admitted to the ICU. The SAPS II score and thrombocytopenia on admission were associated with higher hospital mortality. The characteristics of the metastatic disease, such as number of organs with metastasis and central nervous system metastasis were not associated with the hospital mortality.
P Caruso; A C Ferreira; C E Laurienzo; L N Titton; D S M Terabe; D S Carnieli; D Deheinzelin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-26
Journal Detail:
Title:  European journal of cancer care     Volume:  19     ISSN:  1365-2354     ISO Abbreviation:  Eur J Cancer Care (Engl)     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-05-21     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9301979     Medline TA:  Eur J Cancer Care (Engl)     Country:  England    
Other Details:
Languages:  eng     Pagination:  260-6     Citation Subset:  N    
Hospital A C Camargo, ICU and Respiratory ICU, Pulmonary Division, University of Sao Paulo Medical School, São Paulo, Brazil.
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MeSH Terms
Emergency Service, Hospital
Follow-Up Studies
Intensive Care Units / statistics & numerical data*
Middle Aged
Neoplasms / mortality*
Patient Transfer / statistics & numerical data
Retrospective Studies
Risk Factors
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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