Document Detail


Short and long-term risks to women who conceive through in vitro fertilization.
MedLine Citation:
PMID:  19929571     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There are a number of potential risks to women who conceive through in vitro fertilisation (IVF). Among these, ovarian hyperstimulation syndrome and multiple pregnancies are the most serious. Other potential risks include increased levels of anxiety and depression, ovarian torsion, ectopic pregnancy, pre-eclampsia, placenta praevia, placental separation and increased risk of cesarean section. The association between assisted conception and long-term risk of cancer is debatable. The objective of this review is to critically evaluate the current evidence for potential risks to women who conceive through IVF. To assess the relative risk for any condition, a number of factors need to be taken into account including the method used in identifying the study and control group, the women's characteristics and the number of women included in the study. Many conditions such as ectopic pregnancy and pre-eclampsia appear to be commoner in assisted conception than in spontaneous pregnancy. Nevertheless, the increased risk of these conditions is probably related to the woman's subfertility status and/or increased incidence of multiple pregnancy. Currently, all efforts should concentrate on reduction of multiple births from IVF by restricting the number of transferred embryos.
Authors:
Tarek A Gelbaya
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Human fertility (Cambridge, England)     Volume:  13     ISSN:  1742-8149     ISO Abbreviation:  Hum Fertil (Camb)     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-13     Completed Date:  2010-06-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888143     Medline TA:  Hum Fertil (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  19-27     Citation Subset:  IM    
Affiliation:
Assisted Conception Unit, Kensington Building, Leicester Royal Infirmary, Infirmary Square, Leicester LE1 5WW, UK. tarek.gelbaya@uhl-tr.nhs.uk
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MeSH Terms
Descriptor/Qualifier:
Female
Fertilization in Vitro / adverse effects*
Humans
Ovarian Hyperstimulation Syndrome / etiology*
Ovulation Induction / adverse effects*
Pre-Eclampsia / etiology
Pregnancy
Pregnancy, Ectopic / etiology
Pregnancy, Multiple
Risk
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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