Document Detail

Short and long-term outcomes of percutaneous revascularization in patients with prior coronary artery bypass graft.
MedLine Citation:
PMID:  20485236     Owner:  NLM     Status:  MEDLINE    
AIM: Patients with prior coronary artery bypass grafting (CABG) represent a sizable portion of those undergoing percutaneous coronary intervention (PCI): in many instances, it is unclear whether performing PCI on the bypass graft or in the native coronary vessels can offer the best risk-benefit balance.
METHODS: We included patients with prior CABG undergoing PCI at our center between July 2002 and June 2004 and we distinguished them in three groups. Those in whom PCI was performed on stenotic saphenous vein graft (SVG group), those in whom PCI was performed on native vessels despite the presence of potentially treatable SVG disease (optional native group), and those in whom PCI had to be performed mandatorily in the native vessels because of chronic SVG occlusions or disease in non-bypassed segments (mandatory native group). The primary end-point was long-term rate of major adverse clinical events (MACE, i.e. death, myocardial infarction, or target vessel revascularization).
RESULTS: We identified 109 patients: 28 were in the SVG group, 25 in the optional native group, and 56 in the mandatory native group. Early major adverse cardiac events (MACE) occurred with similar frequency in the three groups (respectively, 9.1%, 0% and 5.7%, P=0.35). After more than three years of follow-up, MACE occurred in 39.3% vs. 28 and 39.4% (P=0.59), death occurred in 27.2 vs. 24.0% vs. 13.5% (P=0.30), and TVR in 27.3% vs. 8.0% vs. 28.8% (P=0.14).
CONCLUSION: In selected patients, PCI of native coronary vessels despite the presence of apparently treatable SVG lesions can be envisioned.
F D'Ascenzo; A Gonella; G Longo; A Pullara; M Bollati; M Vagnarelli; G Biondi Zoccai; C Moretti; F Sciuto; P Omedè; G P Trevi; I Sheiban
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Minerva cardioangiologica     Volume:  58     ISSN:  0026-4725     ISO Abbreviation:  Minerva Cardioangiol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-20     Completed Date:  2010-12-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400725     Medline TA:  Minerva Cardioangiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  291-9     Citation Subset:  IM    
Interventional Cardiology, Division of Cardiology, University of Turin, Turin, Italy.
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MeSH Terms
Angioplasty, Balloon, Coronary*
Constriction, Pathologic / surgery
Coronary Artery Bypass*
Postoperative Complications / surgery*
Retrospective Studies
Saphenous Vein
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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